Cargando…

Bistable, Biphasic Regulation of PP2A-B55 Accounts for the Dynamics of Mitotic Substrate Phosphorylation

The phosphorylation of mitotic proteins is bistable, which contributes to the decisiveness of the transitions into and out of M phase. The bistability in substrate phosphorylation has been attributed to bistability in the activation of the cyclin-dependent kinase Cdk1. However, more recently it has...

Descripción completa

Detalles Bibliográficos
Autores principales: Kamenz, Julia, Gelens, Lendert, Ferrell, James E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7904671/
https://www.ncbi.nlm.nih.gov/pubmed/33357450
http://dx.doi.org/10.1016/j.cub.2020.11.058