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Improving the Methanol Tolerance of an Escherichia coli Methylotroph via Adaptive Laboratory Evolution Enhances Synthetic Methanol Utilization

There is great interest in developing synthetic methylotrophs that harbor methane and methanol utilization pathways in heterologous hosts such as Escherichia coli for industrial bioconversion of one-carbon compounds. While there are recent reports that describe the successful engineering of syntheti...

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Detalles Bibliográficos
Autores principales: Bennett, R. Kyle, Gregory, Gwendolyn J., Gonzalez, Jacqueline E., Har, Jie Ren Gerald, Antoniewicz, Maciek R., Papoutsakis, Eleftherios T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7904680/
https://www.ncbi.nlm.nih.gov/pubmed/33643274
http://dx.doi.org/10.3389/fmicb.2021.638426