Polysialic acid and Siglec-E orchestrate negative feedback regulation of microglia activation

Polysialic acid (polySia) emerges as a novel regulator of microglia activity. We recently identified polysialylated proteins in the Golgi compartment of murine microglia that are released in response to inflammatory stimulation. Since exogenously added polySia is able to attenuate the inflammatory r...

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Detalles Bibliográficos
Autores principales: Thiesler, Hauke, Beimdiek, Julia, Hildebrandt, Herbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7904730/
https://www.ncbi.nlm.nih.gov/pubmed/32725371
http://dx.doi.org/10.1007/s00018-020-03601-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7904730/
https://www.ncbi.nlm.nih.gov/pubmed/32725371
http://dx.doi.org/10.1007/s00018-020-03601-z

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