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Polysialic acid and Siglec-E orchestrate negative feedback regulation of microglia activation
Polysialic acid (polySia) emerges as a novel regulator of microglia activity. We recently identified polysialylated proteins in the Golgi compartment of murine microglia that are released in response to inflammatory stimulation. Since exogenously added polySia is able to attenuate the inflammatory r...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7904730/ https://www.ncbi.nlm.nih.gov/pubmed/32725371 http://dx.doi.org/10.1007/s00018-020-03601-z |