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ORP/Osh mediate cross-talk between ER-plasma membrane contact site components and plasma membrane SNAREs

OSBP-homologous proteins (ORPs, Oshp) are lipid binding/transfer proteins. Several ORP/Oshp localize to membrane contacts between the endoplasmic reticulum (ER) and the plasma membrane, where they mediate lipid transfer or regulate lipid-modifying enzymes. A common way in which they target contacts...

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Detalles Bibliográficos
Autores principales: Weber-Boyvat, Marion, Trimbuch, Thorsten, Shah, Saundarya, Jäntti, Jussi, Olkkonen, Vesa M., Rosenmund, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7904734/
https://www.ncbi.nlm.nih.gov/pubmed/32734583
http://dx.doi.org/10.1007/s00018-020-03604-w