Cargando…

A novel approach for microRNA in situ hybridization using locked nucleic acid probes

Identification of target tissue microRNAs (miR) using in situ hybridization (ISH), with digoxigenin-labeled locked nucleic acid (LNA) probes, is influenced by preanalytic parameters. To determine the best retrieval method for common microRNAs, a multiblock composed of paraffin-embedded tonsil, cervi...

Descripción completa

Detalles Bibliográficos
Autores principales: Paulsen, Isabella W., Bzorek, Michael, Olsen, Jesper, Grum-Schwensen, Birgitte, Troelsen, Jesper T., Pedersen, Ole B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7904755/
https://www.ncbi.nlm.nih.gov/pubmed/33627751
http://dx.doi.org/10.1038/s41598-021-83888-5