Cargando…

Neuregulin signaling mediates the acute and sustained antidepressant effects of subanesthetic ketamine

Subanesthetic ketamine evokes rapid antidepressant effects in human patients that persist long past ketamine’s chemical half-life of ~2 h. Ketamine’s sustained antidepressant action may be due to modulation of cortical plasticity. We find that ketamine ameliorates depression-like behavior in the for...

Descripción completa

Detalles Bibliográficos
Autores principales:	Grieco, Steven F., Qiao, Xin, Johnston, Kevin G., Chen, Lujia, Nelson, Renetta R., Lai, Cary, Holmes, Todd C., Xu, Xiangmin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7904825/ https://www.ncbi.nlm.nih.gov/pubmed/33627623 http://dx.doi.org/10.1038/s41398-021-01255-4

Ejemplares similares

Resurfacing of ketamine: The subanesthetic paradigm
por: Ramachandran, Rashmi, et al.
Publicado: (2016)

Ischemic Postconditioning and Subanesthetic S(+)-Ketamine Infusion: Effects on Renal Function and Histology in Rats
por: de Resende, Marco A. C., et al.
Publicado: (2015)

Subanesthetic ketamine rapidly alters medial prefrontal miRNAs involved in ubiquitin-mediated proteolysis
por: Choi, Yunjung, et al.
Publicado: (2021)

Subanesthetic ketamine infusions for the treatment of children and adolescents with chronic pain: a longitudinal study
por: Sheehy, Kathy A., et al.
Publicado: (2015)

Factors Influencing the Cardiovascular Response to Subanesthetic Ketamine: A Randomized, Placebo-Controlled Trial
por: Liebe, Thomas, et al.
Publicado: (2017)

Castration of Dogs Using Local Anesthesia After Sedating With Xylazine and Subanesthetic Doses of Ketamine
por: Silva, Erika, et al.
Publicado: (2020)

Subanesthetic dose of ketamine for the antidepressant effects and the associated cognitive impairments of electroconvulsive therapy in elderly patients—A randomized, double‐blind, controlled clinical study
por: Zou, Lei, et al.
Publicado: (2020)

Structural Integrity in the Sustained Antidepressant Effect of Ketamine
por: Belujon, Pauline
Publicado: (2017)

Measuring acute effects of subanesthetic ketamine on cerebrovascular hemodynamics in humans using TD-fNIRS
por: Castillo, Adelaida, et al.
Publicado: (2023)

Impact of subanesthetic doses of ketamine on AMPA-mediated responses in rats: An in vivo electrophysiological study on monoaminergic and glutamatergic neurons
por: El Iskandrani, Kareem S, et al.
Publicado: (2015)

Resting-state brain functional connectivity in patients with chronic pain who responded to subanesthetic-dose ketamine
por: Motoyama, Yasushi, et al.
Publicado: (2019)

Reduced auditory evoked gamma-band response and schizophrenia-like clinical symptoms under subanesthetic ketamine
por: Curic, Stjepan, et al.
Publicado: (2019)

Effects of subanesthetic intravenous ketamine infusion on neuroplasticity-related proteins in male and female Sprague-Dawley rats
por: Zhang, Michael, et al.
Publicado: (2021)

Cortical Acetylcholine Levels Correlate With Neurophysiologic Complexity During Subanesthetic Ketamine and Nitrous Oxide Exposure in Rats
por: Brito, Michael A., et al.
Publicado: (2021)

Effects of a Subanesthetic Ketamine Infusion on Inflammatory and Behavioral Outcomes after Closed Head Injury in Rats
por: Spencer, Haley F., et al.
Publicado: (2023)

Effects of Subanesthetic Ketamine Administration on Visual and Auditory Event-Related Potentials (ERP) in Humans: A Systematic Review
por: Schwertner, André, et al.
Publicado: (2018)

Subanesthetic ketamine for pain management in hospitalized children, adolescents, and young adults: a single-center cohort study
por: Sheehy, Kathy A, et al.
Publicado: (2017)

Hippocampal Perineuronal Nets Are Required for the Sustained Antidepressant Effect of Ketamine
por: Donegan, Jennifer J, et al.
Publicado: (2016)

Sustained antidepressant effect of ketamine through NMDAR trapping in the LHb
por: Ma, Shuangshuang, et al.
Publicado: (2023)

Case Reports Showing a Long-Term Effect of Subanesthetic Ketamine Infusion in Reducing l-DOPA-Induced Dyskinesias
por: Sherman, Scott J., et al.
Publicado: (2016)

Case Report of Subanesthetic Intravenous Ketamine Infusion for the Treatment of Neuropathic Pain and Depression with Suicidal Features in a Pediatric Patient
por: Weber, Garret, et al.
Publicado: (2018)

Effects of subanesthetic intravenous ketamine infusion on neuroplasticity-related proteins in the prefrontal cortex, amygdala, and hippocampus of Sprague-Dawley rats
por: Zhang, Michael, et al.
Publicado: (2019)

Efficacy of intraoperative subanesthetic dose of ketamine/esketamine in preventing postoperative cognitive dysfunction: a systematic review and meta-analysis
por: Zhou, Na, et al.
Publicado: (2023)

The olfactory bulb is a source of high-frequency oscillations (130–180 Hz) associated with a subanesthetic dose of ketamine in rodents
por: Hunt, Mark Jeremy, et al.
Publicado: (2018)

Single subanesthetic dose of ketamine produces delayed impact on brain [(18)F]FDG PET imaging and metabolic connectivity in rats
por: Chaib, Sarah, et al.
Publicado: (2023)

Ketamine: stimulating antidepressant treatment?
por: Malhi, Gin S., et al.
Publicado: (2016)

Immunoregulation and antidepressant effect of ketamine
por: Zhang, Nan, et al.
Publicado: (2021)

Author Correction: Sustained antidepressant effect of ketamine through NMDAR trapping in the LHb
por: Ma, Shuangshuang, et al.
Publicado: (2023)

TrkB dependent adult hippocampal progenitor differentiation mediates sustained ketamine antidepressant response
por: Ma, Zhenzhong, et al.
Publicado: (2017)

Effects of intra-operative administration of subanesthetic s-ketamine on emergence from sevoflurane anesthesia: a randomized double-blind placebo-controlled study
por: Liu, Tiantian, et al.
Publicado: (2023)

IGF-1 release in the medial prefrontal cortex mediates the rapid and sustained antidepressant-like actions of ketamine
por: Deyama, Satoshi, et al.
Publicado: (2022)

R-ketamine: a rapid-onset and sustained antidepressant without psychotomimetic side effects
por: Yang, C, et al.
Publicado: (2015)

Comparison of efficacy of three subanesthetic doses of ketamine in allaying procedural discomfort during establishment of subarachnoid block: A randomized double-blind trial
por: Kumar, V. R. Hemanth, et al.
Publicado: (2015)

The Ketamine Antidepressant Story: New Insights
por: Alshammari, Tahani K.
Publicado: (2020)

The role of dissociation in ketamine’s antidepressant effects
por: Ballard, Elizabeth D., et al.
Publicado: (2020)

The antidepressant properties of ketamine (literature review)
por: Chamsi, F. Z., et al.
Publicado: (2023)

A randomized, double-blind, active placebo-controlled study of efficacy, safety, and durability of repeated vs single subanesthetic ketamine for treatment-resistant depression
por: Shiroma, Paulo R., et al.
Publicado: (2020)

Antidepressant effects of ketamine: mechanisms underlying fast-acting novel antidepressants
por: Browne, Caroline A., et al.
Publicado: (2013)

Correction: R-ketamine: a rapid-onset and sustained antidepressant without psychotomimetic side effects
por: Yang, C., et al.
Publicado: (2020)

Microglial ERK-NRBP1-CREB-BDNF signaling in sustained antidepressant actions of (R)-ketamine
por: Yao, Wei, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_t9dsoc362j9q514qk7u8gpgtv8