The effect of ivermectin alone and in combination with cobicistat or elacridar in experimental Schistosoma mansoni infection in mice

Schistosoma mansoni is less susceptible to the antiparasitic drug ivermectin than other helminths. By inhibiting the P-glycoprotein or cytochrome P450 3A in mice host or parasites in a murine model, we aimed at increasing the sensitivity of S. mansoni to the drug and thus preventing infection. We as...

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Detalles Bibliográficos
Autores principales: Vicente, Belén, López-Abán, Julio, Chaccour, Juliane, Hernández-Goenaga, Juan, Nicolas, Patricia, Fernández-Soto, Pedro, Muro, Antonio, Chaccour, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7904857/
https://www.ncbi.nlm.nih.gov/pubmed/33627744
http://dx.doi.org/10.1038/s41598-021-84009-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7904857/
https://www.ncbi.nlm.nih.gov/pubmed/33627744
http://dx.doi.org/10.1038/s41598-021-84009-y

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