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IL-4 and IL-17 Are Required for House Dust Mite-Driven Airway Hyperresponsiveness in Autoimmune Diabetes-Prone Non-Obese Diabetic Mice

Allergic asthma is characterized by airway inflammation with a Th2-type cytokine profile, hyper-IgE production, mucus hypersecretion, and airway hyperreactivity (AHR). It is increasingly recognized that asthma is a heterogeneous disease implicating complex immune mechanisms resulting in distinct end...

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Detalles Bibliográficos
Autores principales: Foray, Anne-Perrine, Dietrich, Céline, Pecquet, Coralie, Machavoine, François, Chatenoud, Lucienne, Leite-de-Moraes, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7904896/
https://www.ncbi.nlm.nih.gov/pubmed/33643284
http://dx.doi.org/10.3389/fimmu.2020.595003