Isoliquiritigenin Confers Neuroprotection and Alleviates Amyloid-β42-Induced Neuroinflammation in Microglia by Regulating the Nrf2/NF-κB Signaling

BACKGROUND: Neuroinflammation and oxidative stress are two major pathological characteristics of Alzheimer’s disease (AD). Amyloid-β oligomers (AβO), a toxic form of Aβ, promote the neuroinflammation and oxidative stress in the development of AD. Isoliquiritigenin (ISL), a natural flavonoid isolated...

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Detalles Bibliográficos
Autores principales: Fu, Yue, Jia, Jianping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7904903/
https://www.ncbi.nlm.nih.gov/pubmed/33642990
http://dx.doi.org/10.3389/fnins.2021.638772

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7904903/
https://www.ncbi.nlm.nih.gov/pubmed/33642990
http://dx.doi.org/10.3389/fnins.2021.638772

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