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Activation of BDNF by transcription factor Nrf2 contributes to antidepressant-like actions in rodents

The transcription factor erythroid 2-related factor 2 (Nrf2) and brain-derived neurotrophic factor (BDNF) play a key role in depression. However, the molecular mechanisms underlying the crosstalk between Nrf2 and BDNF in depression remain unclear. We examined whether Nrf2 regulates the transcription...

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Detalles Bibliográficos
Autores principales: Yao, Wei, Lin, Song, Su, Jin, Cao, Qianqian, Chen, Yueyue, Chen, Jiaxu, Zhang, Zhentao, Hashimoto, Kenji, Qi, Qi, Zhang, Ji-chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7904924/
https://www.ncbi.nlm.nih.gov/pubmed/33627628
http://dx.doi.org/10.1038/s41398-021-01261-6