C-Glucosylation as a tool for the prevention of PAINS-induced membrane dipole potential alterations

The concept of Pan-Assay Interference Compounds (PAINS) is regarded as a threat to the recognition of the broad bioactivity of natural products. Based on the established relationship between altered membrane dipole potential and transmembrane protein conformation and function, we investigate here po...

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Detalles Bibliográficos
Autores principales: de Matos, Ana Marta, Blázquez-Sánchez, Maria Teresa, Sousa, Carla, Oliveira, Maria Conceição, de Almeida, Rodrigo F. M., Rauter, Amélia P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7904931/
https://www.ncbi.nlm.nih.gov/pubmed/33627687
http://dx.doi.org/10.1038/s41598-021-83032-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7904931/
https://www.ncbi.nlm.nih.gov/pubmed/33627687
http://dx.doi.org/10.1038/s41598-021-83032-3

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