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C-Glucosylation as a tool for the prevention of PAINS-induced membrane dipole potential alterations
The concept of Pan-Assay Interference Compounds (PAINS) is regarded as a threat to the recognition of the broad bioactivity of natural products. Based on the established relationship between altered membrane dipole potential and transmembrane protein conformation and function, we investigate here po...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7904931/ https://www.ncbi.nlm.nih.gov/pubmed/33627687 http://dx.doi.org/10.1038/s41598-021-83032-3 |