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MiR-132-3p Modulates MEKK3-Dependent NF-κB and p38/JNK Signaling Pathways to Alleviate Spinal Cord Ischemia-Reperfusion Injury by Hindering M1 Polarization of Macrophages

Spinal cord ischemia-reperfusion (SCIR) injury is a serious complication of open surgical and endovascular aortic procedures. MicroRNA-132-3p (miR-132-3p) has been reported to be involved in the progression of various diseases, but its role in SCIR injury is unclear. Thus, we aimed in this study to...

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Detalles Bibliográficos
Autores principales: Fang, Hua, Li, Hua-Feng, Pan, Qin, Jin, Hon-Ling, Yang, Miao, Wang, Ru-Rong, Wang, Quan-Yun, Zhang, Jian-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7905026/
https://www.ncbi.nlm.nih.gov/pubmed/33644040
http://dx.doi.org/10.3389/fcell.2021.570451