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Senescent Mesenchymal Stem Cells in Myelodysplastic Syndrome: Functional Alterations, Molecular Mechanisms, and Therapeutic Strategies

Myelodysplastic syndrome (MDS) is a group of clonal hematopoietic disorders related to hematopoietic stem and progenitor cell dysfunction. However, therapies that are currently used to target hematopoietic stem cells are not effective. These therapies are able to slow the evolution toward acute myel...

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Detalles Bibliográficos
Autores principales: Chen, Xiaofang, Li, Ningyu, Weng, Jianyu, Du, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7905046/
https://www.ncbi.nlm.nih.gov/pubmed/33644035
http://dx.doi.org/10.3389/fcell.2020.617466