Mutant p53 Gain-of-Function: Role in Cancer Development, Progression, and Therapeutic Approaches

Frequent p53 mutations (mutp53) not only abolish tumor suppressor capacities but confer various gain-of-function (GOF) activities that impacts molecules and pathways now regarded as central for tumor development and progression. Although the complete impact of GOF is still far from being fully under...

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Detalles Bibliográficos
Autores principales: Alvarado-Ortiz, Eduardo, de la Cruz-López, Karen Griselda, Becerril-Rico, Jared, Sarabia-Sánchez, Miguel Angel, Ortiz-Sánchez, Elizabeth, García-Carrancá, Alejandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7905058/
https://www.ncbi.nlm.nih.gov/pubmed/33644030
http://dx.doi.org/10.3389/fcell.2020.607670

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7905058/
https://www.ncbi.nlm.nih.gov/pubmed/33644030
http://dx.doi.org/10.3389/fcell.2020.607670

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