Nitric oxide produced by NOS2 copes with the cytotoxic effects of superoxide in macrophages

Nitric oxide (NO) reacts with superoxide to produce peroxynitrite, a potent oxidant and reportedly exerts cytotoxic action. Herein we validated the hypothesis that interaction of NO with superoxide exerts protection against superoxide toxicity using macrophages from mice with a knockout (KO) of indu...

Descripción completa

Detalles Bibliográficos
Autores principales: Kobayashi, Sho, Homma, Takujiro, Fujii, Junichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7905073/
https://www.ncbi.nlm.nih.gov/pubmed/33665378
http://dx.doi.org/10.1016/j.bbrep.2021.100942

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7905073/
https://www.ncbi.nlm.nih.gov/pubmed/33665378
http://dx.doi.org/10.1016/j.bbrep.2021.100942

Ejemplares similares