Cargando…
Nitric oxide produced by NOS2 copes with the cytotoxic effects of superoxide in macrophages
Nitric oxide (NO) reacts with superoxide to produce peroxynitrite, a potent oxidant and reportedly exerts cytotoxic action. Herein we validated the hypothesis that interaction of NO with superoxide exerts protection against superoxide toxicity using macrophages from mice with a knockout (KO) of indu...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7905073/ https://www.ncbi.nlm.nih.gov/pubmed/33665378 http://dx.doi.org/10.1016/j.bbrep.2021.100942 |