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Peptidoglycan Switches Off the TLR2-Mediated Sperm Recognition and Triggers Sperm Localization in the Bovine Endometrium

In mammals, the uterine mucosal immune system simultaneously recognizes and reacts to most bacteria as well as allogenic sperm mainly through the Toll-like receptors (TLR)2/4 signaling pathway. Here, we characterized the impact of pathogen-derived TLR2/4 ligands (peptidoglycan (PGN)/lipopolysacchari...

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Detalles Bibliográficos
Autores principales: Elesh, Ibrahim Fouad, Marey, Mohamed Ali, Zinnah, Mohammed Ali, Akthar, Ihshan, Kawai, Tomoko, Naim, Fayrouz, Goda, Wael, Rawash, Abdel Rahman A., Sasaki, Motoki, Shimada, Masayuki, Miyamoto, Akio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7905083/
https://www.ncbi.nlm.nih.gov/pubmed/33643300
http://dx.doi.org/10.3389/fimmu.2020.619408