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SH3KBP1 Promotes Glioblastoma Tumorigenesis by Activating EGFR Signaling

Glioblastoma (GBM) is the most common and aggressive brain tumor in adults. Overexpression or activation of epidermal growth factor receptor (EGFR) occurs commonly in multiple human cancers and promotes tumorigenesis. However, the underlying molecular mechanism of EGFR aberrant activation and the do...

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Detalles Bibliográficos
Autores principales: Song, Hai, Wang, Yanpei, Shi, Chaojia, Lu, Jianxiang, Yuan, Tian, Wang, Xiangpeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7905166/
https://www.ncbi.nlm.nih.gov/pubmed/33643898
http://dx.doi.org/10.3389/fonc.2020.583984