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An Improved Genome-Wide Polygenic Score Model for Predicting the Risk of Type 2 Diabetes

Polygenic risk score (PRS) has been shown to be predictive of disease risk such as type 2 diabetes (T2D). However, the existing studies on genetic prediction for T2D only had limited predictive power. To further improve the predictive capability of the PRS model in identifying individuals at high T2...

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Detalles Bibliográficos
Autores principales: Liu, Wei, Zhuang, Zhenhuang, Wang, Wenxiu, Huang, Tao, Liu, Zhonghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7905203/
https://www.ncbi.nlm.nih.gov/pubmed/33643391
http://dx.doi.org/10.3389/fgene.2021.632385