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ORMDL2 Deficiency Potentiates the ORMDL3-Dependent Changes in Mast Cell Signaling

The systemic anaphylactic reaction is a life-threatening allergic response initiated by activated mast cells. Sphingolipids are an essential player in the development and attenuation of this response. De novo synthesis of sphingolipids in mammalian cells is inhibited by the family of three ORMDL pro...

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Detalles Bibliográficos
Autores principales: Bugajev, Viktor, Halova, Ivana, Demkova, Livia, Cernohouzova, Sara, Vavrova, Petra, Mrkacek, Michal, Utekal, Pavol, Draberova, Lubica, Kuchar, Ladislav, Schuster, Björn, Draber, Petr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7905224/
https://www.ncbi.nlm.nih.gov/pubmed/33643282
http://dx.doi.org/10.3389/fimmu.2020.591975