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A cohesive look at leukemogenesis: The cohesin complex and other driving mutations in AML

Acute myeloid leukemia (AML) affects tens of thousands of patients a year, yet survival rates are as low as 25% in certain populations. This poor survival rate is partially due to the vast genetic diversity of the disease. Rarely do 2 patients with AML have the same mutational profile, which makes t...

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Detalles Bibliográficos
Autores principales: Heimbruch, Katelyn E., Meyer, Alison E., Agrawal, Puja, Viny, Aaron D., Rao, Sridhar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7905235/
https://www.ncbi.nlm.nih.gov/pubmed/33621854
http://dx.doi.org/10.1016/j.neo.2021.01.003