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Pellino1 promoted inflammation in lung injury model of sepsis by TRAF6/ NF-κB signal pathway

BACKGROUND: This study was designed to investigate the role of Pellino1 in lung injury model of sepsis and its anti-inflammation mechanism. METHOD: C57BL/6 male mice (6–7 weeks old) and Pellino1(−/−) male mice were subjected to laparotomy followed by extracorporeal cecum mobilization and ligation. T...

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Detalles Bibliográficos
Autores principales: Liu, Xiaqing, Lin, Zhengfang, Xu, Yufeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7905563/
https://www.ncbi.nlm.nih.gov/pubmed/33632252
http://dx.doi.org/10.1186/s12950-021-00276-6