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Exosome-mediated transfer of CD44 from high-metastatic ovarian cancer cells promotes migration and invasion of low-metastatic ovarian cancer cells

OBJECTIVE: To investigate the detailed roles and mechanisms of tumor-derived exosomes in progression and metastasis of ovarian cancer in vitro. METHODS: Exosomes were isolated by differential centrifugation method; the morphology, size and biological markers of exosomes were separately defined by tr...

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Detalles Bibliográficos
Autores principales: Shen, Xiameng, Wang, Conghui, Zhu, Huihui, Wang, Yaping, Wang, Xinyu, Cheng, Xiaodong, Ge, Wanzhong, Lu, Weiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7905574/
https://www.ncbi.nlm.nih.gov/pubmed/33627162
http://dx.doi.org/10.1186/s13048-021-00776-2