Dominant mutations in MIEF1 affect mitochondrial dynamics and cause a singular late onset optic neuropathy

Inherited optic neuropathies are the most common mitochondrial diseases, leading to neurodegeneration involving the irreversible loss of retinal ganglion cells, optic nerve degeneration and central visual loss. Importantly, properly regulated mitochondrial dynamics are critical for maintaining cellu...

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Detalles Bibliográficos
Autores principales: Charif, Majida, Wong, Yvette C., Kim, Soojin, Guichet, Agnès, Vignal, Catherine, Zanlonghi, Xavier, Bensaid, Philippe, Procaccio, Vincent, Bonneau, Dominique, Amati-Bonneau, Patrizia, Reynier, Pascal, Krainc, Dimitri, Lenaers, Guy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7905578/
https://www.ncbi.nlm.nih.gov/pubmed/33632269
http://dx.doi.org/10.1186/s13024-021-00431-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7905578/
https://www.ncbi.nlm.nih.gov/pubmed/33632269
http://dx.doi.org/10.1186/s13024-021-00431-w

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