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The effect of temperature on the stability of PCSK-9 monoclonal antibody: an experimental study

BACKGROUND: PCSK9 monoclonal antibody lowers plasma PCSK9 and LDL-cholesterol levels. The manufacturers recommend drug storage at 2–8 °C, and not above 25 °C. This study aimed to investigate drug stability at various temperatures that this drug could be exposed to during medication handling and tran...

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Detalles Bibliográficos
Autores principales: Kongmalai, Tanawan, Chuanchaiyakul, Nalinee, Sripatumtong, Chattip, Tansit, Tunsuda, Srinoulprasert, Yuttana, Klinsukon, Nareerak, Thongtang, Nuntakorn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7905620/
https://www.ncbi.nlm.nih.gov/pubmed/33632254
http://dx.doi.org/10.1186/s12944-021-01447-3