G-quadruplexes: a promising target for cancer therapy

DNA and RNA can fold into a variety of alternative conformations. In recent years, a particular nucleic acid structure was discussed to play a role in malignant transformation and cancer development. This structure is called a G-quadruplex (G4). G4 structure formation can drive genome instability by...

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Detalles Bibliográficos
Autores principales: Kosiol, Nils, Juranek, Stefan, Brossart, Peter, Heine, Annkristin, Paeschke, Katrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7905668/
https://www.ncbi.nlm.nih.gov/pubmed/33632214
http://dx.doi.org/10.1186/s12943-021-01328-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7905668/
https://www.ncbi.nlm.nih.gov/pubmed/33632214
http://dx.doi.org/10.1186/s12943-021-01328-4

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