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Salidroside and isorhamnetin attenuate urotensin II-induced inflammatory response in vivo and in vitro: Involvement in regulating the RhoA/ROCK II pathway

Urotensin II (UII), a vital vasoconstrictor peptide, causes an inflammatory response in the pathogenesis of atherosclerosis. Previous studies have reported that the Ras homolog gene family, member A (RhoA)/Rho kinases (ROCK) pathway modulates the inflammatory response of the atherosclerotic process....

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Detalles Bibliográficos
Autores principales: Wang, Chenjing, Nan, Xiaodong, Pei, Shuyan, Zhao, Yu, Wang, Xiaokun, Ma, Shijie, Ma, Guoyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7905674/
https://www.ncbi.nlm.nih.gov/pubmed/33732368
http://dx.doi.org/10.3892/ol.2021.12553