Plasma mitochondrial DNA levels are associated with acute lung injury and mortality in septic patients

BACKGROUND: Mitochondrial DNA (mtDNA) is a critical activator of inflammation. Circulating mtDNA released causes lung injury in experimental models. We hypothesized that elevated plasma mtDNA levels are associated with acute lung injury (ALI) in septic patients. METHODS: We enrolled 66 patients with...

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Detalles Bibliográficos
Autores principales: Mao, Jia-yu, Li, Dong-kai, Zhang, Hong-min, Wang, Xiao-ting, Liu, Da-wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7905766/
https://www.ncbi.nlm.nih.gov/pubmed/33632166
http://dx.doi.org/10.1186/s12890-021-01437-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7905766/
https://www.ncbi.nlm.nih.gov/pubmed/33632166
http://dx.doi.org/10.1186/s12890-021-01437-2

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