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Plasma mitochondrial DNA levels are associated with acute lung injury and mortality in septic patients
BACKGROUND: Mitochondrial DNA (mtDNA) is a critical activator of inflammation. Circulating mtDNA released causes lung injury in experimental models. We hypothesized that elevated plasma mtDNA levels are associated with acute lung injury (ALI) in septic patients. METHODS: We enrolled 66 patients with...
Autores principales: | Mao, Jia-yu, Li, Dong-kai, Zhang, Hong-min, Wang, Xiao-ting, Liu, Da-wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7905766/ https://www.ncbi.nlm.nih.gov/pubmed/33632166 http://dx.doi.org/10.1186/s12890-021-01437-2 |
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