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DMTMM-Mediated Intramolecular Cyclization of Acidic Residues in Peptides/Proteins

[Image: see text] The formation of succinimide in proteins has attracted considerable attention in protein aging and biopharmaceutical research. The succinimide formation occurs spontaneously in proteins and is prone to hydrolysis to yield aspartate and isoaspartate, resulting in altered protein fun...

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Detalles Bibliográficos
Autores principales: Lee, Chi-Hua, Lou, Yuan-Chao, Wang, Andrew H.-J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7905807/
https://www.ncbi.nlm.nih.gov/pubmed/33644578
http://dx.doi.org/10.1021/acsomega.0c05503