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DMTMM-Mediated Intramolecular Cyclization of Acidic Residues in Peptides/Proteins
[Image: see text] The formation of succinimide in proteins has attracted considerable attention in protein aging and biopharmaceutical research. The succinimide formation occurs spontaneously in proteins and is prone to hydrolysis to yield aspartate and isoaspartate, resulting in altered protein fun...
Autores principales: | Lee, Chi-Hua, Lou, Yuan-Chao, Wang, Andrew H.-J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7905807/ https://www.ncbi.nlm.nih.gov/pubmed/33644578 http://dx.doi.org/10.1021/acsomega.0c05503 |
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