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Regulating the immunosuppressive tumor microenvironment to enhance breast cancer immunotherapy using pH-responsive hybrid membrane-coated nanoparticles

The combination of an immuno-metabolic adjuvant and immune checkpoint inhibitors holds great promise for effective suppression of tumor growth and invasion. In this study, a pH-responsive co-delivery platform was developed for metformin (Met), a known immuno-metabolic modulator, and short interferin...

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Detalles Bibliográficos
Autores principales: Gong, Chunai, Yu, Xiaoyan, Zhang, Wei, Han, Lu, Wang, Rong, Wang, Yujie, Gao, Shen, Yuan, Yongfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7905864/
https://www.ncbi.nlm.nih.gov/pubmed/33632231
http://dx.doi.org/10.1186/s12951-021-00805-8