Spatial Regulation of T-Cell Signaling by Programmed Death-Ligand 1 on Wireframe DNA Origami Flat Sheets

[Image: see text] Programmed Death-1 (PD-1) is a coinhibitory receptor expressed on activated T cells that suppresses T-cell signaling and effector functions. It has been previously shown that binding to its ligand PD-L1 induces a spatial reorganization of PD-1 receptors into microclusters on the ce...

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Detalles Bibliográficos
Autores principales: Fang, Trixy, Alvelid, Jonatan, Spratt, Joel, Ambrosetti, Elena, Testa, Ilaria, Teixeira, Ana I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7905882/
https://www.ncbi.nlm.nih.gov/pubmed/33556239
http://dx.doi.org/10.1021/acsnano.0c10632

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7905882/
https://www.ncbi.nlm.nih.gov/pubmed/33556239
http://dx.doi.org/10.1021/acsnano.0c10632

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