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Deposition of the Membrane Attack Complex in Healthy and Diseased Human Kidneys

The membrane attack complex—also known as C5b-9—is the end-product of the classical, lectin, and alternative complement pathways. It is thought to play an important role in the pathogenesis of various kidney diseases by causing cellular injury and tissue inflammation, resulting in sclerosis and fibr...

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Detalles Bibliográficos
Autores principales: Koopman, Jacob J. E., van Essen, Mieke F., Rennke, Helmut G., de Vries, Aiko P. J., van Kooten, Cees
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7906018/
https://www.ncbi.nlm.nih.gov/pubmed/33643288
http://dx.doi.org/10.3389/fimmu.2020.599974