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Deposition of the Membrane Attack Complex in Healthy and Diseased Human Kidneys
The membrane attack complex—also known as C5b-9—is the end-product of the classical, lectin, and alternative complement pathways. It is thought to play an important role in the pathogenesis of various kidney diseases by causing cellular injury and tissue inflammation, resulting in sclerosis and fibr...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7906018/ https://www.ncbi.nlm.nih.gov/pubmed/33643288 http://dx.doi.org/10.3389/fimmu.2020.599974 |