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Ageing transcriptome meta-analysis reveals similarities and differences between key mammalian tissues

By combining transcriptomic data with other data sources, inferences can be made about functional changes during ageing. Thus, we conducted a meta-analysis on 127 publicly available microarray and RNA-Seq datasets from mice, rats and humans, identifying a transcriptomic signature of ageing across sp...

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Detalles Bibliográficos
Autores principales: Palmer, Daniel, Fabris, Fabio, Doherty, Aoife, Freitas, Alex A., de Magalhães, João Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7906136/
https://www.ncbi.nlm.nih.gov/pubmed/33611312
http://dx.doi.org/10.18632/aging.202648