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PRMT5 regulates colorectal cancer cell growth and EMT via EGFR/Akt/GSK3β signaling cascades

Emerging evidence shows that type II protein arginine methyltransferase 5 (PRMT5) serves as an oncoprotein and plays a critical role in many types of human cancer. However, the precise role and function of PRMT5 in human colorectal cancer (CRC) growth and epithelial-mesenchymal transition (EMT) are...

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Detalles Bibliográficos
Autores principales: Yan, Yongrong, Zhao, Peipei, Wang, Zihuan, Liu, Zhen, Wang, Zhizhi, Zhang, Jinglan, Ding, Yanqing, Hua, Xing, Yu, Lina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7906165/
https://www.ncbi.nlm.nih.gov/pubmed/33495409
http://dx.doi.org/10.18632/aging.202407