The roles of PARP-1 and XPD and their potential interplay in repairing bupivacaine-induced neuron oxidative DNA damage

Bupivacaine has been widely used in clinical Anesthesia, but its neurotoxicity has been frequently reported, implicating cellular oxidative DNA damage as the major underlying mechanism. However, the mechanism underlying bupivacaine-induced oxidative DNA damage is unknown. We, thus, exposed SH-SY5Y c...

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Detalles Bibliográficos
Autores principales: Zhao, Wei, Liu, Zhongjie, Luo, Jiaming, Ma, Changqing, Lai, Luying, Xia, Zhengyuan, Xu, Shiyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7906168/
https://www.ncbi.nlm.nih.gov/pubmed/33495403
http://dx.doi.org/10.18632/aging.202390

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7906168/
https://www.ncbi.nlm.nih.gov/pubmed/33495403
http://dx.doi.org/10.18632/aging.202390

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