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The roles of PARP-1 and XPD and their potential interplay in repairing bupivacaine-induced neuron oxidative DNA damage
Bupivacaine has been widely used in clinical Anesthesia, but its neurotoxicity has been frequently reported, implicating cellular oxidative DNA damage as the major underlying mechanism. However, the mechanism underlying bupivacaine-induced oxidative DNA damage is unknown. We, thus, exposed SH-SY5Y c...
Autores principales: | Zhao, Wei, Liu, Zhongjie, Luo, Jiaming, Ma, Changqing, Lai, Luying, Xia, Zhengyuan, Xu, Shiyuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7906168/ https://www.ncbi.nlm.nih.gov/pubmed/33495403 http://dx.doi.org/10.18632/aging.202390 |
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