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Adipose-derived stromal cells improve functional recovery after spinal cord injury through TGF-β1/Smad3/PLOD2 pathway activation

Transplantation of mesenchymal stromal cells (MSCs) improves functional recovery in experimental models of spinal cord injury (SCI), but the mechanism is not fully understood. Activation of procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 (PLOD2), a collagen-modifying enzyme, reportedly follows MS...

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Detalles Bibliográficos
Autores principales: Li, Fang, Liu, Hua, Zhang, Kun, Xiao, Dong-Jie, Wang, Chang, Wang, Yun-Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7906172/
https://www.ncbi.nlm.nih.gov/pubmed/33495412
http://dx.doi.org/10.18632/aging.202399