Cargando…
The age pattern of the male-to-female ratio in mortality from COVID-19 mirrors that of cardiovascular disease in the general population
Males are at a higher risk of dying from COVID-19 than females. Older age and cardiovascular disease are also associated with COVID-19 mortality. To better understand how age and sex interact (in) contributing to COVID-19 mortality, we stratified the male-to-female (sex) ratios in mortality by age g...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7906174/ https://www.ncbi.nlm.nih.gov/pubmed/33550276 http://dx.doi.org/10.18632/aging.202639 |
_version_ | 1783655240103362560 |
---|---|
author | Nimgaonkar, Ila Valeri, Linda Susser, Ezra Hussain, Sabiha Sunderram, Jag Aviv, Abraham |
author_facet | Nimgaonkar, Ila Valeri, Linda Susser, Ezra Hussain, Sabiha Sunderram, Jag Aviv, Abraham |
author_sort | Nimgaonkar, Ila |
collection | PubMed |
description | Males are at a higher risk of dying from COVID-19 than females. Older age and cardiovascular disease are also associated with COVID-19 mortality. To better understand how age and sex interact (in) contributing to COVID-19 mortality, we stratified the male-to-female (sex) ratios in mortality by age group. We then compared the age-stratified sex ratios with those of cardiovascular mortality and cancer mortality in the general population. Data were obtained from official government sources in the US and five European countries: Italy, Spain, France, Germany, and the Netherlands. The sex ratio of deaths from COVID-19 exceeded one throughout adult life, increasing up to a peak in midlife, and declining markedly in later life. This pattern was also observed for the sex ratio of deaths from cardiovascular disease, but not cancer, in the general populations of the US and European countries. Therefore, the sex ratios of deaths from COVID-19 and from cardiovascular disease share similar patterns across the adult life course. The underlying mechanisms are poorly understood and warrant further investigation. |
format | Online Article Text |
id | pubmed-7906174 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Impact Journals |
record_format | MEDLINE/PubMed |
spelling | pubmed-79061742021-03-04 The age pattern of the male-to-female ratio in mortality from COVID-19 mirrors that of cardiovascular disease in the general population Nimgaonkar, Ila Valeri, Linda Susser, Ezra Hussain, Sabiha Sunderram, Jag Aviv, Abraham Aging (Albany NY) Research Paper Males are at a higher risk of dying from COVID-19 than females. Older age and cardiovascular disease are also associated with COVID-19 mortality. To better understand how age and sex interact (in) contributing to COVID-19 mortality, we stratified the male-to-female (sex) ratios in mortality by age group. We then compared the age-stratified sex ratios with those of cardiovascular mortality and cancer mortality in the general population. Data were obtained from official government sources in the US and five European countries: Italy, Spain, France, Germany, and the Netherlands. The sex ratio of deaths from COVID-19 exceeded one throughout adult life, increasing up to a peak in midlife, and declining markedly in later life. This pattern was also observed for the sex ratio of deaths from cardiovascular disease, but not cancer, in the general populations of the US and European countries. Therefore, the sex ratios of deaths from COVID-19 and from cardiovascular disease share similar patterns across the adult life course. The underlying mechanisms are poorly understood and warrant further investigation. Impact Journals 2021-02-07 /pmc/articles/PMC7906174/ /pubmed/33550276 http://dx.doi.org/10.18632/aging.202639 Text en Copyright: © 2021 Nimgaonkar et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/3.0/) (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Paper Nimgaonkar, Ila Valeri, Linda Susser, Ezra Hussain, Sabiha Sunderram, Jag Aviv, Abraham The age pattern of the male-to-female ratio in mortality from COVID-19 mirrors that of cardiovascular disease in the general population |
title | The age pattern of the male-to-female ratio in mortality from COVID-19 mirrors that of cardiovascular disease in the general population |
title_full | The age pattern of the male-to-female ratio in mortality from COVID-19 mirrors that of cardiovascular disease in the general population |
title_fullStr | The age pattern of the male-to-female ratio in mortality from COVID-19 mirrors that of cardiovascular disease in the general population |
title_full_unstemmed | The age pattern of the male-to-female ratio in mortality from COVID-19 mirrors that of cardiovascular disease in the general population |
title_short | The age pattern of the male-to-female ratio in mortality from COVID-19 mirrors that of cardiovascular disease in the general population |
title_sort | age pattern of the male-to-female ratio in mortality from covid-19 mirrors that of cardiovascular disease in the general population |
topic | Research Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7906174/ https://www.ncbi.nlm.nih.gov/pubmed/33550276 http://dx.doi.org/10.18632/aging.202639 |
work_keys_str_mv | AT nimgaonkarila theagepatternofthemaletofemaleratioinmortalityfromcovid19mirrorsthatofcardiovasculardiseaseinthegeneralpopulation AT valerilinda theagepatternofthemaletofemaleratioinmortalityfromcovid19mirrorsthatofcardiovasculardiseaseinthegeneralpopulation AT susserezra theagepatternofthemaletofemaleratioinmortalityfromcovid19mirrorsthatofcardiovasculardiseaseinthegeneralpopulation AT hussainsabiha theagepatternofthemaletofemaleratioinmortalityfromcovid19mirrorsthatofcardiovasculardiseaseinthegeneralpopulation AT sunderramjag theagepatternofthemaletofemaleratioinmortalityfromcovid19mirrorsthatofcardiovasculardiseaseinthegeneralpopulation AT avivabraham theagepatternofthemaletofemaleratioinmortalityfromcovid19mirrorsthatofcardiovasculardiseaseinthegeneralpopulation AT nimgaonkarila agepatternofthemaletofemaleratioinmortalityfromcovid19mirrorsthatofcardiovasculardiseaseinthegeneralpopulation AT valerilinda agepatternofthemaletofemaleratioinmortalityfromcovid19mirrorsthatofcardiovasculardiseaseinthegeneralpopulation AT susserezra agepatternofthemaletofemaleratioinmortalityfromcovid19mirrorsthatofcardiovasculardiseaseinthegeneralpopulation AT hussainsabiha agepatternofthemaletofemaleratioinmortalityfromcovid19mirrorsthatofcardiovasculardiseaseinthegeneralpopulation AT sunderramjag agepatternofthemaletofemaleratioinmortalityfromcovid19mirrorsthatofcardiovasculardiseaseinthegeneralpopulation AT avivabraham agepatternofthemaletofemaleratioinmortalityfromcovid19mirrorsthatofcardiovasculardiseaseinthegeneralpopulation |