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Myeloid differentiation 2 deficiency attenuates AngII-induced arterial vascular oxidative stress, inflammation, and remodeling

Vascular remodeling is a pertinent target for cardiovascular therapy. Vascular smooth muscle cell (VSMC) dysfunction plays a key role in vascular remodeling. Myeloid differentiation 2 (MD2), a cofactor of toll-like receptor 4 (TLR4), is involved in atherosclerotic progress and cardiac remodeling via...

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Detalles Bibliográficos
Autores principales: Huang, Shushi, You, Shengban, Qian, Jinfu, Dai, Chengyi, Shen, Siyuan, Wang, Jun, Huang, Weijian, Liang, Guang, Wu, Gaojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7906178/
https://www.ncbi.nlm.nih.gov/pubmed/33495414
http://dx.doi.org/10.18632/aging.202402