Hypoxia-inducible factor 2-alpha-dependent induction of IL-6 protects the heart from ischemia/reperfusion injury

Myocardial ischemia-reperfusion injury (MIRI) results in increased myocardial infarct size and leads to poor clinical outcomes. Hypoxia-inducible factor 2-alpha (HIF2α) exerts myocardial protective effects during MIRI through as yet unclear mechanisms. Here, we show that knockdown of HIF2α with card...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Jia-Wei, Hu, Hao, Li, Dan, Ma, Li-Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7906200/
https://www.ncbi.nlm.nih.gov/pubmed/33428604
http://dx.doi.org/10.18632/aging.202276

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7906200/
https://www.ncbi.nlm.nih.gov/pubmed/33428604
http://dx.doi.org/10.18632/aging.202276

Ejemplares similares