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Hypoxia-inducible factor 2-alpha-dependent induction of IL-6 protects the heart from ischemia/reperfusion injury

Myocardial ischemia-reperfusion injury (MIRI) results in increased myocardial infarct size and leads to poor clinical outcomes. Hypoxia-inducible factor 2-alpha (HIF2α) exerts myocardial protective effects during MIRI through as yet unclear mechanisms. Here, we show that knockdown of HIF2α with card...

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Detalles Bibliográficos
Autores principales:	Wu, Jia-Wei, Hu, Hao, Li, Dan, Ma, Li-Kun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7906200/ https://www.ncbi.nlm.nih.gov/pubmed/33428604 http://dx.doi.org/10.18632/aging.202276

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