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Oxaliplatin induces the PARP1-mediated parthanatos in oral squamous cell carcinoma by increasing production of ROS

Oral squamous cell carcinoma (OSCC) is one of the most common malignant tumors worldwide, and its prognosis is still not optimistic. Oxaliplatin is a type of platinum chemotherapeutic agent, but its treatment effects on OSCC and molecular mechanisms have not been fully elucidated. Parthanatos, a uni...

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Detalles Bibliográficos
Autores principales: Li, Dongfang, Kou, Yuying, Gao, Yuan, Liu, Shanshan, Yang, Panpan, Hasegawa, Tomoka, Su, Rongjian, Guo, Jie, Li, Minqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7906208/
https://www.ncbi.nlm.nih.gov/pubmed/33495407
http://dx.doi.org/10.18632/aging.202386