Site-specific conjugation of native antibody

Traditionally, non-specific chemical conjugations, such as acylation of amines on lysine or alkylation of thiols on cysteines, are widely used; however, they have several shortcomings. First, the lack of site-specificity results in heterogeneous products and irreproducible processes. Second, potenti...

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Detalles Bibliográficos
Autores principales: Sadiki, Amissi, Vaidya, Shefali R, Abdollahi, Mina, Bhardwaj, Gunjan, Dolan, Michael E, Turna, Harpreet, Arora, Varnika, Sanjeev, Athul, Robinson, Timothy D, Koid, Andrea, Amin, Aashka, Zhou, Zhaohui Sunny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7906296/
https://www.ncbi.nlm.nih.gov/pubmed/33644685
http://dx.doi.org/10.1093/abt/tbaa027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7906296/
https://www.ncbi.nlm.nih.gov/pubmed/33644685
http://dx.doi.org/10.1093/abt/tbaa027

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