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Pulsed-electromagnetic-field induced osteoblast differentiation requires activation of genes downstream of adenosine receptors A2A and A3

Pulsed-electromagnetic-field (PEMF) treatment was found to enhance cellular differentiation of the mouse preosteoblast, MC3T3-E1, to a more osteoblastic phenotype. Differentiation genes such as Alp, BSPI, cFos, Ibsp, Osteocalcin, Pthr1 and Runx2 showed increased expression in response to PEMF stimul...

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Detalles Bibliográficos
Autores principales: Kar, Niladri S., Ferguson, Daniel, Zhang, Nianli, Waldorff, Erik I., Ryaby, James T., DiDonato, Joseph A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7906300/
https://www.ncbi.nlm.nih.gov/pubmed/33630907
http://dx.doi.org/10.1371/journal.pone.0247659