Comprehensive in silico analysis and molecular dynamics of the superoxide dismutase 1 (SOD1) variants related to amyotrophic lateral sclerosis

Amyotrophic Lateral Sclerosis (ALS) is the most frequent motor neuron disorder, with a significant social and economic burden. ALS remains incurable, and the only drugs approved for its treatments confers a survival benefit of a few months for the patients. Missense mutations in superoxide dismutase...

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Detalles Bibliográficos
Autores principales: Pereira, Gabriel Rodrigues Coutinho, Vieira, Bárbara de Azevedo Abrahim, De Mesquita, Joelma Freire
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7906464/
https://www.ncbi.nlm.nih.gov/pubmed/33630959
http://dx.doi.org/10.1371/journal.pone.0247841

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7906464/
https://www.ncbi.nlm.nih.gov/pubmed/33630959
http://dx.doi.org/10.1371/journal.pone.0247841

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