Cargando…

Intermedilysin cytolytic activity depends on heparan sulfates and membrane composition

Cholesterol-dependent cytolysins (CDCs), of which intermedilysin (ILY) is an archetypal member, are a group of pore-forming toxins secreted by a large variety of pathogenic bacteria. These toxins, secreted as soluble monomers, oligomerize upon interaction with cholesterol in the target membrane and...

Descripción completa

Detalles Bibliográficos
Autores principales: Drabavicius, Gediminas, Daelemans, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7906465/
https://www.ncbi.nlm.nih.gov/pubmed/33577603
http://dx.doi.org/10.1371/journal.pgen.1009387